Publisert 2023

Les på engelsk


Tidsskrift : Scientific Reports , vol. 13 , p. 1–14 , 2023

Utgiver : Springer Nature

Internasjonale standardnummer :
Trykt : 2045-2322
Elektronisk : 2045-2322

Publikasjonstype : Vitenskapelig artikkel

Bidragsytere : Bøgwald, Isak; Østbye, Tone-Kari K.; Pedersen, Alice Marie; Rønning, Sissel; Dias, Jorge; Eilertsen, Karl-Erik; Wubshet, Sileshi Gizachew

Sak : 1



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Kjetil Aune


The world will be dependent on the development of novel feed ingredients from renewable sources to ensure sustainable growth of the aquaculture industry. Zooplankton like Calanus finmarchicus are viable new raw material candidates, as they have optimal nutrient profiles for aquatic animals and may be sustainably harvested in large volumes. In this study, the aim was to investigate if a protein hydrolysate of C. finmarchicus was able to influence the growth performance of fish. The effect of dietary inclusion of hydrolysates was tested in a feeding trial with European sea bass (Dicentrarchus labrax) juveniles, benchmarking calanus hydrolysate (CH) against commercially available hydrolysates. The diet with CH inclusion yielded increased growth, with significantly higher body weight than hydrolysates of sardine and tuna fish at the end of the trial. The observed growth-promoting effects were further examined using an in vitro model with skeletal muscle cells from Atlantic salmon. Through bioactivity experiments with muscle cells grown in media containing CH, low-molecular fractions were found to have the greatest positive effect on proliferation, viability, and expression of muscle-specific genes. Characterization of the most potent fraction revealed an abundance of small peptides, along with amino acids and marine metabolites associated with increased muscle growth.


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