Nonleaching antimicrobial films prepared from surface modified microfibrillated cellulose
Publikasjonsdetaljer
Tidsskrift : Biomacromolecules , vol. 8 , p. 2149–2155 , 2007
Internasjonale standardnummer
:
Trykt
:
1525-7797
Elektronisk
:
1526-4602
Publikasjonstype : Vitenskapelig artikkel
Lenker
:
DOI
:
doi.org/10.1021/bm070304e
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Kjetil Aune
Bibliotekleder
kjetil.aune@nofima.no
Sammendrag
We have prepared potentially permanent antimicrobial films based on surface-modified microfibrillated cellulose (MFC). MFC, obtained by disintegration of bleached softwood sulfite pulp in a homogenizer, was grafted with the quaternary ammonium compound octadecyldimethyl(3-trimethoxysilylpropyl)ammonium chloride (ODDMAC) by a simple adsorption-curing process. Films prepared from the ODDMAC-modified MFC were characterized by Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) and tested for antibacterial activity against the Gram-positive bacterium Staphylococcus aureus and the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa. The films showed substantial antibacterial capacity even at very low concentrations of antimicrobial agent immobilized on the surface. A zone of inhibition test demonstrated that no ODDMAC diffused into the surroundings, verifying that the films were indeed of the nonleaching type.