Publisert 2013

Les på engelsk


Tidsskrift : European Journal of Nutrition , vol. 52 , p. 799–812 , 2013

Internasjonale standardnummer :
Trykt : 1436-6207
Elektronisk : 1436-6215

Publikasjonstype : Vitenskapelig artikkel

Bidragsytere : Ballance, Simon; Sahlstrøm, Stefan; Lea, Per; Nagy, Nina Elisabeth; Andersen, Petter Vejle; Dessev, Tzvetelin Teodossiev; Hull, Sarah; Vardakou, Maria; Faulks, Richard

Sak : 2

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Kjetil Aune


Purpose: To identify the key parameters involved in cereal starch digestion and associated glycaemic response by the utilisation of a dynamic gastro-duodenal digestion model. Methods: Potential plasma glucose loading curves for each meal were calculated and fitted to an exponential function. The area under the curve (AUC) from 0 to 120 min and total digestible starch was used to calculate an in vitro glycaemic index (GI) value normalised against white bread. Microscopy was additionally used to examine cereal samples collected in vitro at different stages of gastric and duodenal digestion. Results: Where in vivo GI data were available (4 out of 6 cereal meals) no significant difference was observed between these values and the corresponding calculated in vitro GI value. Conclusion: It is possible to simulate an in vivo glycaemic response for cereals when the gastric emptying rate (duodenal loading) and kinetics of digestible starch hydrolysis in the duodenum are known.