Gå til hovedinnhold
Publisert 2003

Read in English

Publikasjonsdetaljer

Tidsskrift : Analytica Chimica Acta , vol. 488 , p. 231–241 , 2003

Utgiver : Elsevier

Internasjonale standardnummer :
Trykt : 0003-2670
Elektronisk : 1873-4324

Publikasjonstype : Vitenskapelig artikkel

Bidragsytere : Mjøs, Svein Are

Har du spørsmål om noe vedrørende publikasjonen, kan du kontakte Nofimas bibliotekleder.

Kjetil Aune
Bibliotekleder
kjetil.aune@nofima.no

Sammendrag

In hyphenated chromatography, overlapping chromatographic peaks can be resolved into pure spectra and pure chromatographic profiles by several multivariate deconvolution techniques. In general, these methods require bilinearity, which implies that the spectrum of each analyte is constant. The slow scan speeds normally used in gas chromatography–mass spectrometry (GC–MS) will destroy bilinearity and introduce systematic noise in the data because the concentration in the detector changes during the scan. This effect, described as the scan effect, may hinder successful resolution by multivariate deconvolution. In selected ion monitoring (SIM) GC–MS, the scan effect may be removed by simple transformations of the mass spectra. The effects of different transformations are demonstrated both on pure chromatographic peaks and on difficult resolution problems where there are small differences between the spectra of the analytes.