Vitenskapelig artikkel

Nonleaching antimicrobial films prepared from surface modified microfibrillated cellulose

Andresen, Martin; Stenstad, Per Martin; Møretrø, Trond; Langsrud, Solveig; Syverud, Kristin; Johansson, Leena-Sisko; Stenius, Per Johan


Tidsskrift: Biomacromolecules, vol. 8, p. 2149–2155, 2007

Internasjonale standardnumre:
Trykt: 1525-7797
Elektronisk: 1526-4602

Open Access: none


We have prepared potentially permanent antimicrobial films based on surface-modified microfibrillated cellulose (MFC). MFC, obtained by disintegration of bleached softwood sulfite pulp in a homogenizer, was grafted with the quaternary ammonium compound octadecyldimethyl(3-trimethoxysilylpropyl)ammonium chloride (ODDMAC) by a simple adsorption-curing process. Films prepared from the ODDMAC-modified MFC were characterized by Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) and tested for antibacterial activity against the Gram-positive bacterium Staphylococcus aureus and the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa. The films showed substantial antibacterial capacity even at very low concentrations of antimicrobial agent immobilized on the surface. A zone of inhibition test demonstrated that no ODDMAC diffused into the surroundings, verifying that the films were indeed of the nonleaching type.