Publikasjonsdetaljer
Tidsskrift: Vaccine, vol. 26, p. 6791–6799, 2008
Utgiver: Elsevier
Utgave: 52
Internasjonale standardnumre:
Trykt: 0264-410X
Elektronisk: 1873-2518
Open Access: none
Lenker:
DOI
Atypical furunculosis caused by atypical Aeromonas salmonicida, is an emerging problem in farming of Atlantic cod (Gadus morhua) in Norway, and vaccines are needed. Atypical A. salmonicida comprises a heterogeneous group of bacteria differing in surface antigens such as the A-layer protein and lipopolysaccharides (LPS). Except for one of the experimental oil-adjuvanted whole cell vaccines based on various isolates they all resulted in moderate protection. No clear correlation between vaccine efficacies and the A-protein group or LPS type of the vaccine isolates was revealed, while a correlation between efficacy and the presence of cross-reacting LPS-specific antibodies is indicated.