Academic article

Gene expression profiles in liver of pigs with extreme high and low levels of androstenone

Moe, Maren; Lien, Sigbjørn; Bendixen, Christian; Hedegaard, Jakob; Hornshøj, Henrik; Berget, Ingunn; Meuwissen, Theodorus; Grindflek, Eli

Publication details

Journal: BMC Veterinary Research, vol. 4, p. 1, 2008

Publisher: BioMed Central (BMC)

International Standard Numbers:
Printed: 1746-6148
Electronic: 1746-6148

Open Access: gold


Conclusion: A number of genes and pathways related to metabolism of androstenone in liver were identified, including new candidate genes involved in phase I oxidation metabolism, phase II conjugation metabolism, and regulation of steroid availability. The study is a first step towards a deeper understanding of enzymes and regulators involved in pathways of androstenone metabolism and may ultimately lead to the discovery of markers to reduce boar taint.