Journal publication » Academic article
Gene expression profiles in liver of pigs with extreme high and low levels of androstenone
BMC Veterinary Research ; Volume 4. p. 2008
Moe, Maren; Lien, Sigbjørn; Bendixen, Christian; Hedegaard, Jakob; Hornshøj, Henrik; Berget, Ingunn; Meuwissen, Theo; Grindflek, Eli
Conclusion: A number of genes and pathways related to metabolism of androstenone in liver were identified, including new candidate genes involved in phase I oxidation metabolism, phase II conjugation metabolism, and regulation of steroid availability. The study is a first step towards a deeper understanding of enzymes and regulators involved in pathways of androstenone metabolism and may ultimately lead to the discovery of markers to reduce boar taint.