Sustainable, Effective and Natural Inhibition of Food-Borne Pathogens by Advanced Phage Technology
The project goal is to establish a technology platform for development of next generation phages in enhanced formulations, to protect food against contamination with Listeria, Salmonella and STEC (Shiga toxin producing E. coli).
|Time:||1. October 2020 – 30. September 2023|
Existing processing aids for food safety, while mostly effective, still cannot prevent antimicrobial resistance and disease outbreaks; imposing huge socio-economic burden due to morbidity, mortality, and product recalls. Further, customers are seeking new interventions for food safety that qualify as clean-label technologies. We aim to ensure food safety via bacteriophages (“phages”); the natural biological control agents against bacteria.
Phages infect and replicate inside specific bacteria, ultimately killing them. By selecting phages that specifically target pathogens, yet are safe for beneficial bacteria, targeted products can be developed to eliminate harmful bacteria, preventing foodborne illnesses. The main results of the project will be a completed technology platform for next generation phages in improved phage formulations, and demonstration of three prototype products as food processing aids. To achieve this, we will select specific phages and develop prototype products which will be validated for efficacy. Prototype phage formulations will be validated in spice-blends/marinades and dry-salted cold-smoked salmon.