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Biography Tone-Kari K. Østbye

I work with muscle quality and nutrition in Atlantic salmon focusing on muscle deformity, muscle structural and muscle regulatory factors, oxidative stress, apoptosis, and fatty acid metabolism. I make use of techniques like cell culturing, quantitative PCR, microarray, cloning, immunocytochemistry, and Western blotting. I received a master degree in biotechnology from the University in Tromsø and the master thesis in medical genetics from the University Hospital North Norway. My doctoral degree within molecular fish biology and muscle regulatory factors in Atlantic salmon is from Nofima Marin (formerly Institute of Aquaculture Research) and the Norwegian University of Life Sciences.

Tone-Kari K. Østbye has 55 publications at Nofima:

North Atlantic fish oils and importance for utilization of omega-3 fatty acids

Østbye, Tone-Kari K; Berge, Gerd Marit; Krasnov, Aleksei; Romarheim, Odd Helge; Nilsson, Astrid; Hansen, Marianne Helén Selander; Burdge, Graham C.; Irvine, Nicola A.; Ruyter, Bente

2020

Nofima reports

Lipid Deposition and Mobilisation in Atlantic Salmon Adipocytes

Bou, Marta; Wang, Xinxia; Todorcevic, Marijana; Østbye, Tone-Kari K; Torgersen, Jacob Seilø; Ruyter, Bente

2020

Academic article

Application of Molecular Methods in Aquaculture and Fishery

Dulić, Zorka; Rašković, Božidar; Marić, Saša; Østbye, Tone-Kari K

2019

Academic chapter/article/Conference paper

Oils for healthier salmon and humans

Østbye, Tone-Kari K; Nilsson, Astrid

2019

Popular scientific article

Dietary Fish Oil Alters DNA Methylation of Genes Involved in Polyunsaturated Fatty Acid Biosynthesis in Muscle and Liver of Atlantic Salmon (Salmo salar)

Irvine, Nicola A.; Ruyter, Bente; Østbye, Tone-Kari K; Sonesson, Anna Kristina; Lillycrop, Karen A.; Berge, Gerd Marit; Burdge, Graham C.

2019

Academic article

The long-chain monounsaturated cetoleic acid improves the efficiency of the n-3 fatty acid metabolic pathway in Atlantic salmon and human HepG2 cells

Østbye, Tone-Kari K; Berge, Gerd Marit; Nilsson, Astrid; Romarheim, Odd Helge; Bou, Marta; Ruyter, Bente

2019

Academic article

The possible involvement of oxidative stress in the oocyte ageing process in goldfish Carassius auratus (Linnaeus, 1758)

Samarin, Azadeh Mohagheghi; Samarin, Azin Mohagheghi; Østbye, Tone-Kari K; Ruyter, Bente; Sempels, Sabine; Burkina, Viktoriia; Blecha, Miroslav; Policar, Tomas

2019

Academic article

n-3 canola oil effectively replaces fish oil as a new safe dietary source of DHA in feed for juvenile Atlantic salmon

Ruyter, Bente; Sissener, Nini; Østbye, Tone-Kari K; Simon, Cedric; Krasnov, Aleksei; Bou, Marta; Sanden, Monica; Nichols, Peter D.; Lutfi Royo, Esmail; Berge, Gerd Marit

2019

Academic article

Effect of feed, temperature and stress on pigmentation in salmon

Ytrestøyl, Trine; Dikiy, Alexander; Shumulina, Elena; Bæverfjord, Grete; Krasnov, Aleksei; Ciampa, Alessandra; Hatlen, Bjarne; Østbye, Tone-Kari K; Bou, Marta; Dessen, Jens-Erik; Rørvik, Kjell-Arne; Ruyter, Bente

2019

Nofima reports

New omega-3 sources in diets of Atlantic salmon

Ruyter, Bente; Kousoulaki, Katerina; Krasnov, Aleksei; Sissener, Nini; Simon, Cedric; Mørkøre, Turid; Bou, Marta; Østbye, Tone-Kari K; Bæverfjord, Grete; Sanden, Monica; Romarheim, Odd Helge; Carlehög, Mats; Ytrestøyl, Trine; Lutfi Royo, Esmail; Berge, Gerd Marit

2019

Nofima reports

Importance of nutrition for skin, intestine and gill health in Atlantic salmon

Berge, Gerd Marit; Ytteborg, Elisabeth; Østbye, Tone-Kari K; Sundh, Henrik; Rud, Ida; Sveen, Lene; Bæverfjord, Grete; Karlsen, Christian; Krasnov, Aleksei; Øgaard, Jonas; Sundell, Kristina; Pedersen, Mona Elisabeth; Halvorsen, Bente; Ruyter, Bente

2019

Nofima reports

Alteration of mRNA abundance, oxidation products and antioxidant enzyme activities during oocyte ageing in common carp Cyprinus carpio

Samarin, Azin Mohagheghi; Samarin, Azadeh Mohagheghi; Østbye, Tone-Kari K; Ruyter, Bente; Sampels, Sabine; Burkina, Viktoriia; Blecha, Miroslav; Gela, David; Policar, Tomas

2019

Academic article

Dietary impacts of sulphuric acid extracted fish bone compounds on astaxanthin utilization and muscle quality in Atlantic salmon (Salmo salar)

Albrektsen, Sissel; Østbye, Tone-Kari K; Pedersen, Mona Elisabeth; Ytteborg, Elisabeth; Ruyter, Bente; Ytrestøyl, Trine

2018

Academic article

Effects of tetradecylthioacetic acid (TTA) treatment on lipid metabolism in salmon hearts—in vitro and in vivo studies

Arge, Regin; Dessen, Jens-Erik; Østbye, Tone-Kari K; Ruyter, Bente; Thomassen, Magny Sissel S.; Rørvik, Kjell-Arne

2018

Academic article

Functional amino acids stimulate muscle development and improve fillet texture of Atlantic salmon

Østbye, Tone-Kari K; Ruyter, Bente; Standal, Inger Beate; Stien, Lars Helge; Bahuaud, Diane; Dessen, Jens-Erik; Latif, Muhammad Saqib; Terjesen, Bendik Fyhn; Rørvik, Kjell-Arne; Mørkøre, Turid

2018

Academic article

The role of extracellular matrix components in pin bone attachments during storage-a comparison between farmed Atlantic salmon (Salmo salar) and cod (Gadus morhua L.).

Rønning, Sissel Beate; Østbye, Tone-Kari K; Krasnov, Aleksei; Vuong, Tram Thu; Veiseth-Kent, Eva; Pedersen, Mona Elisabeth

2017

Academic article

Low levels of very-long-chain n-3 PUFA in Atlantic salmon (Salmo salar) diet reduce fish robustness under challenging conditions in sea cages

Bou, Marta; Berge, Gerd Marit; Bæverfjord, Grete; Sigholt, Trygve; Østbye, Tone-Kari K; Ruyter, Bente

2017

Academic article

EPA, DHA, and Lipoic Acid Differentially Modulate the n-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes

Bou, Marta ; Østbye, Tone-Kari K; Berge, Gerd Marit; Ruyter, Bente

2017

Academic article

Requirements of n-3 very long-chain PUFA in Atlantic salmon (Salmo salar L): effects of different dietary levels of EPA and DHA on fish performance and tissue composition and integrity

Bou, Marta; Berge, Gerd Marit; Bæverfjord, Grete; Sigholt, Trygve; Østbye, Tone-Kari K; Romarheim, Odd Helge; Hatlen, Bjarne; Leeuwis, Robin; Venegas, Claudia; Ruyter, Bente

2017

Academic article

Regulation of the Omega-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes

Kjær, Marte Avranden; Ruyter, Bente; Berge, Gerd Marit; Sun, Yajing; Østbye, Tone-Kari K

2016

Academic article

The role of extracellular matrix components in pin bone attachments during storage—a comparison between farmed Atlantic salmon (Salmo salar) and cod (Gadus morhua L.)

Rønning, Sissel Beate; Østbye, Tone-Kari K; Krasnov, Aleksei; Vuong, Tram Thu; Veiseth-Kent, Eva; Kolset, Svein Olav; Pedersen, Mona Elisabeth

2016

Academic article

Vil ketolinsyre (22:1n-11) fra lodde-, sild- og tobisolje føre til bedret utnyttelse av omega-3 fettsyrer?

Ruyter, Bente; Østbye, Tone-Kari K; Romarheim, Odd Helge; Nilsson, Astrid; Kristiansen, Inger Øien; Bjerke, Målfrid Tofteberg; Bergum, Silje; Berge, Gerd Marit

2016

Nofima reports

Effekter av endret fettsyresammensetning i fôr til laks relatert til fiskens helse, velferd og robusthet (Fett for fiskehelse): Oppdatering 2016

Sissener, Nini; Torstensen, Bente Elisabeth; Ruyter, Bente; Østbye, Tone-Kari K; Waagbø, Rune; Jørgensen, Sven Martin; Hatlen, Bjarne; Liland, Nina Sylvia; Ytteborg, Elisabeth; Sæle, Øystein; Rud, Ida; Remø, Sofie C.; Mørkøre, Turid; Dessen, Jens-Erik; Skjerven, Kaja; Ytrestøyl, Trine; Holen, Elisabeth; Berge, Gerd Marit; Adam, Anne-Catrin

2016

Report

Rapport/Report 26/2016 – English summary

Ruyter, Bente; Bou, Marta; Bæverfjord, Grete; Østbye, Tone-Kari K; Ytrestøyl, Trine; Bjerke, Målfrid Tofteberg; Sigholt, Trygve; Berge, Gerd Marit

2016

Nofima reports

Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae

Kousoulaki, Katerina; Østbye, Tone-Kari K; Krasnov, Aleksei; Torgersen, Jacob Seilø; Mørkøre, Turid; Sweetman, John W.

2015

Academic article

Rapport/Report 7/2015 English summary

Ruyter, Bente; Østbye, Tone-Kari K; Kjær, Marte Avranden; Sonesson, Anna Kristina; Mørkøre, Turid; Berge, Gerd Marit

2015

Nofima reports

Rapport/Report 8/2015 english summary

Berge, Gerd Marit; Østbye, Tone-Kari K; Kjær, Marte Avranden; Sonesson, Anna Kristina; Mørkøre, Turid; Ruyter, Bente

2015

Nofima reports

Rapport/Report 9/2015 English summary

Østbye, Tone-Kari K; Berge, Gerd Marit; Sonesson, Anna Kristina; Krasnov, Aleksei; Ruyter, Bente

2015

Nofima reports

N-3 fatty acid intake altered fat content and fatty acid distribution in chicken breast muscle, but did not influence mRNA expression of lipid-related enzymes

Haug, Anna; Nyquist, Nicole Frost; Thomassen, Magny S.; Høstmark, Arne Torbjørn; Østbye, Tone-Kari K

2014

Academic article

Rapport/Report 10/2014 English summary

Østbye, Tone-Kari K; Ruyter, Bente; Kristiansen, Inger Øien; Albrektsen, Sissel

2014

Nofima reports

Rapport/Report 21/2014 English summary

Pedersen, Mona Elisabeth; Vuong, Tram Thu; Østbye, Tone-Kari K; Veiseth-Kent, Eva; Larsson, Thomas; Hollung, Kristin; Kolset, Svein Olav; Rønning, Sissel Beate

2014

Nofima reports

Fett for fiskehelse. Utredning: Effekter av endret fettsyre-sammensetning i fôr til laks relatert til fiskens helse, velferd og robusthet

Torstensen, Bente Elisabeth; Ruyter, Bente; Sissener, Nini; Østbye, Tone-Kari K; Waagbø, Rune; Jørgensen, Sven Martin; Ytteborg, Elisabeth; Rud, Ida; Liland, Nina Sylvia; Mørkøre, Turid; Dessen, Jens-Erik

2013

Report

Laksens helse, velferd og robusthet påvirkes av fettsyresammensetning i fôr

Torstensen, Bente Elisabeth; Ruyter, Bente; Sissener, Nini; Østbye, Tone-Kari K; Waagbø, Rune; Jørgensen, Sven Martin; Ytteborg, Elisabeth; Rud, Ida; Liland, Nina Sylvia; Mørkøre, Turid; Dessen, Jens-Erik

2013

Article in business/trade/industry journal

Kombinasjon av høye nivåer av vegetabilske fôroljer og lav sjøtemperatur; Sett i sammenheng med vekst og dødelighet hos regnbueørret i Nord

van Nes, Solveig; Østbye, Tone-Kari K; Ruyter, Bente; Dessen, Jens-Erik; Kristiansen, Inger Øien; Bjerke, Målfrid Tofteberg; Rørvik, Kjell-Arne

2013

Nofima reports

Lagringsstabilitet av et utvalg marine oljer. Effekt av oljekvalitet på cellulære responser – Fase 2

Grimmer, Stine J Staavi; Østbye, Tone-Kari K; Ruyter, Bente; Vogt, Kjell gjermund; Haugen, John-erik

2013

Nofima reports

Effects of dietary supplementation of coriander oil, in canola oil diets, on the metabolism of [1-14C] 18:3n-3 and [1-14C] 18:2n-6 in rainbow trout hepatocytes

Randall, Kyla M.; Drew, Murray D.; Øverland, Margareth; Østbye, Tone-Kari K; Bjerke, Målfrid Tofteberg; Vogt, Kjell gjermund; Ruyter, Bente

2013

Academic article

Kunnskap- og metodeutvikling for å styrke laksens robusthet og helse

Jørgensen, Sven Martin; Sørensen, Mette; Torgersen, Jacob; Todorcevic, Marijana; Østbye, Tone-Kari K; Aas-Hansen, Øyvind; Johansen, Lill-Heidi; Timmerhaus, Gerrit; Bao, Marta; Alarcon, Marta; Mørkøre, Turid; Krasnov, Aleksei; Ruyter, Bente; Takle, Harald Rune

2012

Nofima reports

High dietary EPA does not inhibit Delta 5 and Delta 6 desaturases in Atlantic salmon (Salmo salar L.) fed rapeseed oil diets

Thomassen, Magny S.; Rein, Dietrich; Berge, Gerd Marit; Østbye, Tone-Kari K; Ruyter, Bente

2012

Academic article

Gene Expression Profiling of Soft and Firm Atlantic Salmon Fillet

Larsson, Thomas; Mørkøre, Turid; Kolstad, Kari; Østbye, Tone-Kari K; Afanasyev, Sergey; Krasnov, Aleksei

2012

Academic article

In vivo and in vitro insulin and fasting control of the transmembrane fatty acid transport proteins in Atlantic salmon (Salmo salar)

Sánchez-Gurmaches, Joan; Østbye, Tone-Kari K; Navarro, Isabel; Torgersen, Jacob; Hevrøy, Ernst Morten; Ruyter, Bente; Torstensen, Bente Elisabeth

2011

Academic article

Influence of Dietary Sesamin, a Bioactive Compound on Fatty Acids and Expression of Some Lipid Regulating Genes in Baltic Atlantic Salmon (Salmo salar L.) Juveniles

Trattner, S.; Ruyter, Bente; Østbye, Tone-Kari K; Kamal-Eldin, A.; Moazzami, A.; Pan, J.; Gjøen, Tor; Brännäs, E.; Zlabek, V.; Pickova, J.

2011

Academic article

High n-3 HUFA levels in the diet of Atlantic salmon affect muscle and mitochondrial membrane lipids and their susceptibility to oxidative stress

Østbye, Tone-Kari K; Kjær, Marte Avranden; Rørå, Anna Maria Bencze; Torstensen, Bente Elisabeth; Ruyter, Bente

2011

Academic article

Atlantic salmon (Salmo salar L.) flesh quality - role of lysosomal cathepsins B and L in muscle degradation

Bahuaud, Diane; Mørkøre, Turid; Østbye, Tone-Kari K; Torstensen, Bente Elisabeth; Veiseth-Kent, Eva; Ruyter, Bente; Ofstad, Ragni; Thomassen, Magny S.

2010

Academic chapter/article/Conference paper

Atlantic salmon (Salmo salar) muscle precursor cells differentiate into osteoblasts in vitro: Polyunsaturated fatty acids and hyperthermia influence gene expression and differentiation

Ytteborg, Elisabeth; Vegusdal, Anne; Witten, P.Eckhard; Berge, Gerd Marit; Takle, Harald Rune; Østbye, Tone-Kari K; Ruyter, Bente

2010

Academic article

Identification of a novel allele of peroxisome proliferator-activated receptor gamma (PPARG) and its association with resistance to Aeromonas salmonicida in Atlantic salmon (Salmo salar)

Sundvold, Hilde; Ruyter, Bente; Østbye, Tone-Kari K; Moen, Thomas

2010

Academic article

Muscle structure responses and lysosomal cathepsins B and L in farmed Atlantic salmon (Salmo salar L.) pre- and post-rigor fillets exposed to short and long-term crowding stress

Bahuaud, Diane; Mørkøre, Turid; Østbye, Tone-Kari K; Veiseth-Kent, Eva; Thomassen, Magny S.; Ofstad, Ragni

2010

Academic article

Atlantic salmon (Salmo salar) muscle structure integrity and lysosomal cathepsins B and L influenced by dietary n-6 and n-3 fatty acids

Bahuaud, Diane; Østbye, Tone-Kari K; Torstensen, Bente Elisabeth; Rørå, Mia B.; Ofstad, Ragni; Veiseth, Eva; Thomassen, Magny Skinlo; Ruyter, Bente

2009

Academic article

Sesamin Increases Alpha-Linolenic Acid Conversion to Docosahexaenoic Acid in Atlantic Salmon (Salmo salar L.) Hepatocytes: Role of Altered Gene Expression

Trattner, Sofia; Ruyter, Bente; Østbye, Tone-Kari K.; Gjøen, Tor; Zlabek, V; Kamal-Eldin, A; Pickova, J

2008

Academic article

Molecular cloning of the Atlantic salmon activin receptor IIB cDNA - Localization of the receptor and myostatin in vivo and in vitro in muscle cells

Østbye, Tone-Kari K; Andersen, Øivind; Frang, Ola T; Tooming-Klunderud, Ave; Jakobsen, Kjetill S.; Yafe, Anat; Etzioni, Shulamit; Moen, Thomas

2007

Academic article

Myostatin (MSTN) gene duplications in Atlantic salmon (Salmo salar): Evidence for different selective pressure on teleost MSTN-1 and -2

Østbye, Tone-Kari K; Wetten, Ola F.; Tooming-Klunderud, Ave ; Jakobsen, Kjetill Sigurd; Yafe, Anat; Etzioni, Shulamit; Moen, Thomas; Andersen, Øivind

2007

Academic article

Molecular cloning of the Atlantic salmon activin receptor IIB cDNA - Localization of the receptor and myostatin in vivo and in vitro in muscle cells

Østbye, Tone-Kari K; Bardal, Tora; Vegusdal, Anne; Frang, Ola T.; Kjørsvik, Elin; Andersen, Øivind

2007

Academic article

Molecular characterization of a PDZ–LIM protein in Atlantic salmon (Salmo salar): a fish ortholog of the α-actinin-associated LIM-protein (ALP)

Andersen, Øivind; Østbye, Tone-Kari K; Gabestad, Irene; Nielsen, Christer; Bardal, Tora; Galloway, Trina Falck

2004

Academic article

Molecular characterization of a PDZ-LIM protein in Atlantic salmon (Salmo salar): a fish ortholog of the alpha-actinin-associated LIM-protein (ALP)

Østbye, Tone-Kari K; Andersen, Øivind; Gabestad, Irene; Nielsen, Christer; Bardal, Tora; Galloway, Trina

2004

Academic article

Beta-oxidation, esterification, and secretion of radiolabeled fatty acids in cultivated Atlantic salmon skeletal muscle cells

Vegusdal, Anne; Østbye, Tone-Kari K; Tran, TN; Gjøen, Tor; Ruyter, B

2004

Academic article

The two myostatin genes of Atlantic salmon (Salmo salar) are expressed in a variety of tissues

Østbye, Tone-Kari K; Galloway, Trina; Nielsen, Christer; Gabestad, Irene; Bardal, Tora; Andersen, Øivind

2001

Academic article